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International Journal of Homoeopathic Sciences
2020, Vol. 4 Issue 2, Part D
Analysis of the performance of the ultra-diluted Viscum album in cultivation of mesenchymal stem cells and mammary adenocarcinoma cells pmc-42 and mcf-7
Author(s): Ana Catarina Viana Valle, Lana Ribeiro Aguiar, Hilana Dos Santos Sena Brunel, Patricia Furtado Malard and Rosângela Vieira De Andrade
Abstract:
Adenocarcinoma in breast can be of several types and PMC-42 and MCF-7 cell lines are a well-established cell lines used in in vitro studies retaining much of the breast's native phenotype. Viscum album, a plant which extract has cytotoxic effects, is included in the brand-new class of cancer therapies and its ultra-diluted version is a promising area of interest. The MTT assay was realized to evaluate the cytotoxic potential and calculate the inhibitory concentration of different concentrations of ultra-diluted Viscum album D30 (VAD30). The results indicated that 60mL/mL, 37mL/mL and 35ml/mL of VAD30 were cytotoxic to 50% of mesenchymal stem cell, MCF-7 and PMC-42 cells respectively. This result shows the better potency of action of VAD30 against tumor cells, as a lower concentration inhibits the growing of this cell line in comparison to health cells, demonstrating that this medicine has the potential to be used in cancer therapy.
Adenocarcinoma in breast can be of several types and PMC-42 and MCF-7 cell lines are a well-established cell lines used in in vitro studies retaining much of the breast's native phenotype. Viscum album, a plant which extract has cytotoxic effects, is included in the brand-new class of cancer therapies and its ultra-diluted version is a promising area of interest. The MTT assay was realized to evaluate the cytotoxic potential and calculate the inhibitory concentration of different concentrations of ultra-diluted Viscum album D30 (VAD30). The results indicated that 60mL/mL, 37mL/mL and 35ml/mL of VAD30 were cytotoxic to 50% of mesenchymal stem cell, MCF-7 and PMC-42 cells respectively. This result shows the better potency of action of VAD30 against tumor cells, as a lower concentration inhibits the growing of this cell line in comparison to health cells, demonstrating that this medicine has the potential to be used in cancer therapy.
Pages: 279-283 | 1773 Views 694 Downloads
How to cite this article:
Ana Catarina Viana Valle, Lana Ribeiro Aguiar, Hilana Dos Santos Sena Brunel, Patricia Furtado Malard, Rosângela Vieira De Andrade. Analysis of the performance of the ultra-diluted Viscum album in cultivation of mesenchymal stem cells and mammary adenocarcinoma cells pmc-42 and mcf-7. Int J Hom Sci 2020;4(2):279-283. DOI: 10.33545/26164485.2020.v4.i2d.179
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International Journal of Homoeopathic Sciences
