Abstract: The Pancreas was generally ignored both as an organ of physiological importance and as a seat of disease. Older Physicians and pathologists reported different pancreatic disorders after dissecting human cadavers. Porcine pancreatic transplants were attempted in Europe, as pigs were considered to be good candidates for xenotransplants. A survey on the recent medical literature signifies a steady rise in pancreatic transplants. Persons with their pancreas in a morbid state, exhibit a variety of emotions that will vary according to the type of pathology. Johann Gottfried Rademacher, the modern father of organopathy, although a contemporary to Hahnemann, adopted the doctrines of Paracelsus and introduced many specific remedies into Homoeopathic practice. The extensive works of O A Julian are perceived from his books ‘Materia Medica of new Homoeopathic remedies' and ‘Materia medica of Nosodes with Repertory'. An insight into the Homoeopathic remedies that correspond to the treatment of pancreatic diseases is compiled with reference from the available Homoeopathic literature. This attempt may be a steppingstone for formulating a well-designed research protocol in place of conventional surgical management or the rising pancreatic transplants.