Abstract: Homoeopathy, a conventional complementary and alternative therapy, is used by many cancerous patients but its mechanism and action has not been explored yet also these medicine are effective in low doses. Anti-cancerous role of Homoeopathic medicine is under search. These medicine are supposed to be anti-cancerous as they cause malignant cell death or size deduction by inhibition of proliferative cells, apoptotic signally, enhancing mitochondrial membrane permeability and lowering cancer marker enzymes. Ruta, Thuja 200c and Hydrastis, Lycopodium 1M inhibit nitrosodiethylamine and used in brain cell glial growth. Conium inhibit substage G of cell cycle and also AKT and NF-KB leading toward apoptosis pathway and it is anti- tumorous against breast cancer. Sabal serrulata activates NF-KB apoptotic pathway and inhibit 5-alpha reductase and treat BPH. Medicines like Ruta, Thuja, Carcinosin modulate immunity and protective against cancer. Chelidonium lowers the cancer marker enzymes and cause Necrosis treating hepatocellular carcinoma. Viscum Album increased the survival rate in pancreatic cancerous patient. Cadmium Chloride in low potency reduced the size of brain stem tumor in boy. Lycopodium in male patient in 30c increased the life span and relieved the pain of inguinal hernia and adenocarcinoma. Podophyllum possess anti-prostate cancer potential. Natrum sulph 200c reduced cytological and genetical aberration induced by carcinogens. Condurango is used against stomach cancer. Gelsemium with silver nanoparticles precipitate showed anti-proliferative of skin melanoma. Psorinum is effective against human lung cancer. Sulphur is effective against non-small cell lung carcinoma.