Abstract:Background: Migraine is known to be a major cause of difficulty and disability affecting the daily work in approximately 15% of women and 6% of men among the population. It is usually an episodic headache associated with nausea, vomiting and other neurological symptoms.
Aim: This study aims to explore the efficacy of homoeopathic medicines in the treatment of migraine.
Methodology: Study design was a single-blind placebo-controlled randomized clinical trial. Total 60 patients were included in the study after screening and assigned to two groups i.e. test group (n=30) and control group (n=30). The test group received homoeopathic medicines and control group received identical placebo. For intensity assessment Headache Impact test (HIT 6) was used. HIT scores were recorded before and after treatment. The duration of the study was 6 months.
Results: Females were more commonly affected than males and the incidence was higher in the second and fourth decades of life and lower in elderly people. Paired t-test was applied to observe the difference in groups and found statistically significant (p<0.0001). The most frequent prescribed homoeopathic medicine was Natrum muriaticum. Onosmodium and Prunus spinosa were also frequently prescribed in acute conditions. Less indicated remedies were Lachesis, Sulphur, Silicea, Pulsatilla, Lycopodium, Spigelia and Sanguinaria.
Conclusion: Homoeopathic medicines found effective in the treatment of migraine in this study. more studies with larger sample size are suggested.