International Journal of Homoeopathic Sciences

Aim: To assess the Role of homeopathic medicine Kali Cyanatum 30C in improving post radiation oral mucositis in cases of oral squamous cell carcinoma.

Study design: Double arm Prospective study had been conducted with 30 cases of post radiation oral mucositis. Cases were divided in two groups. Each group consisted of 15 subjects. Group A was treated with homeopathic medicine Kali Cyanatum 30C for 12 weeks while group B was given standard treatment. Results were evaluated using clinical examination and photographic records.

Results: After one month, in the treatment group 4 out of 10 grade IV patients became grade 1 while only 1 remained grade IV. After 60 days all grade IV became either grade I or grade 0. After 60 days out of 5, 3 grade III became grade 0.After 2 months all patients became either grade 0 or I.

In the placebo group after 30 days out of 8 grade IV, 6 remain grade IV. 5 out of 7 grade III remains grade III, even one progressed to grade IV.

After 60 days 2 out of 8 grade IV patients become grade I and none become grade 0 while 4 out of 7 grade III become grade II, and 3 of grade 3 become grade I.

Conclusion: Kali Cyanatum 30C improved radiation induced oral mucositis in cases of oral squamous cell carcinoma. But more scientific studies are needed in future to establish its role in palliative care.