International Journal of Homoeopathic Sciences

Background: In the human intestine, Escherichia coli, also known as E. Coli, is a prevalent bacterium. The specific strain of E. Coli responsible for Urinary Tract Infections (UTIs) is referred to as Uropathogenic E. Coli (UPEC). Recent results from the Global Antimicrobial Surveillance System (GLASS) conducted by the WHO reveal a troubling prevalence of antibiotic resistance, with E. Coli standing out as the most frequently documented resistant bacteria. Cantharis is one of the most profoundly prescribed Homoeopathic medicines in case of UTIs in clinical practice. This study focuses on assessing the in vitro antibacterial action of the Homeopathic medicine Cantharis against Uropathogenic E. Coli.

Materials and Methods: The Homoeopathic Medicine Cantharis in Q, 30 C, 200 C, and 1M was tested for antibacterial activity using the Kirby-Bauer Disk Diffusion test. The colonies of the uropathogenic strain of E. Coli were cultured in nutrient broth and inoculated on Muller-Hinton Agar plates. The discs impregnated with Homoeopathic medicine Cantharis in Q, 30 C, 200 C, 1 M and Vehicle control (Ethanol 90%) were placed in MHA plates and left for 24 hours at 37 ^oC after which the zone of inhibition was measured.

Results: The zone of growth inhibition around Cantharis Q, 30C, 200 C, 1 M, and control was (1.6±0.1) c.m., (1.6±0.1) c.m., (0.8±0.1) c.m., (0.6±0.1) c.m. and 0.6 c.m. respectively.

Conclusion: Cantharis Q and 30 C exhibited the maximum Growth Inhibitory Zone against Escherichia coli, compared to the control.