International Journal of Homoeopathic Sciences

Ethambutol-Induced Optic Neuropathy (EON) is a known complication of ethambutol therapy, commonly used in the treatment of tuberculosis. EON is characterized by visual acuity loss, color vision disturbances, and visual field defects, which can significantly impair a patient's daily life. Conventional treatment involves discontinuing ethambutol and providing supportive care, but alternative therapies such as homeopathy are being explored for their potential benefits. This case series of EON is managed with homeopathic remedies, specifically Physostigma and Natrum Muriaticum. A patient was presented with typical symptoms of EON, including reduced visual acuity. When there was persistent visual loss even 2 years after discontinuation of ethambutol, a homeopathic regimen was initiated, incorporating Physostigma and Natrum Muriaticum based on the patient's symptomatology and constitutional type. As a result, notable improvements in visual function were seen. These findings suggest that homeopathic management with Physostigma and Natrum Muriaticum may offer a supportive role in the recovery from EON. However, comprehensive clinical trials and further research are essential to confirm these results and elucidate the mechanisms through which these homeopathic treatments may exert their effects.