The molecular basis of exercise: A key to lifestyle disease management
Author(s): Ajeesha Vasudevan and Preetha B
Abstract: The molecular basis of exercise provides a compelling framework for understanding its therapeutic potential in managing lifestyle diseases such as obesity, type 2 diabetes, cardiovascular disorders, and metabolic syndrome. According to World Health Organization (WHO) data, approximately 61% of global deaths and 49% of the global disease burden are attributed to lifestyle diseases. The proportion of deaths resulting from lifestyle disease is expected to increase to 70% globally by 2030. Regular physical activity modulates gene expression, enhances insulin sensitivity, promotes fatty acid oxidation, and reduces chronic inflammation, all of which are critical in mitigating the progression of lifestyle-related disorders. This review aims to enhance understanding of the molecular basis of exercise, contributing to the development of more effective treatment strategies for managing lifestyle-related diseases.
Ajeesha Vasudevan, Preetha B. The molecular basis of exercise: A key to lifestyle disease management. Int J Hom Sci 2024;8(4):441-443. DOI: 10.33545/26164485.2024.v8.i4g.1322