International Journal of Homoeopathic Sciences

Background: Lachesis muta, commonly known as the bushmaster snake, is a venomous species found predominantly in the rainforests of Central and South America. It belongs to the Kingdom Animalia under Viperidae family, Genus Lachesis, and Species muta. It is the largest pit viper in the Western Hemisphere and is notable for its potent venom and elusive behavior.

The venom of Lachesis muta is a complex biochemical mixture that includes SVMPs, serine proteases, PLA₂, and LAAOs. These components act synergistically to produce local tissue necrosis, hemorrhage, coagulopathy, and inflammatory responses. The venom’s systemic effects on cardiovascular and immune systems make it an object of interest in toxicological research.

In homeopathy, Lachesis muta has been transformed from a toxic substance to a polychrest remedy, extensively used for a broad range of ailments. Introduced into the homeopathic materia medica by Dr. Constantine Hering.

Objective: To explore the toxicological composition of Lachesis muta venom, its clinical utility in homeopathy using the similia principle and their action.

Methods: This article integrates data from toxicological research, classical homeopathic materia medica, and clinical literature accessed through PubMed, Google Scholar, and Homeopathy360.

Results: Lachesis venom contains enzymatic proteins causing hemorrhage, inflammation, and neurotoxicity. Potentized forms are used homeopathically in conditions with similar presentations, especially those with left-sided affinity. Lachesis muta demonstrates a powerful convergence of toxicity and therapeutic utility, providing a foundation for integrative research.