International Journal of Homoeopathic Sciences

RBC aplasia is a rare hematologic condition characterized by a severe reduction in erythroid precursors in the bone marrow, leading to anaemia. Pure red cell aplasia (PRCA) can be congenital or acquired and may result from autoimmune disorders, viral infections, malignancies, or drug-induced bone marrow suppression. This paper explores the pathophysiology, clinical presentation, diagnostic approach, and comprehensive management of RBC aplasia, with a particular focus on individualized homeopathic treatment based on symptomatology and constitutional approach. The research also presents a few representative case studies from the Advanced Homoeo Health Centre, Indore, where patients showed hematologic improvement under classical homeopathic care.