International Journal of Homoeopathic Sciences

Belladonna (Atropa belladonna), a commonly used homoeopathic remedy, is traditionally known for its mydriatic effects i.e., the ability to dilate the pupil. This study was conducted to evaluate the effect of Belladonna in 5X potency on the eye of a rabbit. Drugs affecting the eye are classified into myotics (pupil contracting), mydriatics (pupil dilating), and cycloplegics. For the experiment, a healthy rabbit was selected, with its right eye serving as the control and its left eye designated for testing. Belladonna 5X (aqueous preparation) was instilled in the left eye, and observations were made at five-minute intervals. Pupil diameter, corneal reflex, light reflex, and conjunctival color were recorded. Results indicated that Belladonna 5X produced noticeable dilation of the pupil, confirming its mydriatic action. This experiment supports the traditional pharmacological understanding of Belladonna and provides an observational basis for its effect in homoeopathic dosage, particularly within physiological models like that of the rabbit eye.