International Journal of Homoeopathic Sciences

Introduction: Anal fissures are an extremely common disease with a severe impact on patients quality of life. The main goal of anal fissure treatment is rapid pain relief and long-lasting healing.
Aim: Controversies and disagreement exist on conventional treatment strategies of Anal fissures due to relapse, inefficacy, and complications. We intend to evaluate the role of individualized homeopathic treatment in Anal fissures.
Materials and Methods: In this prospective, open level, observational trial, Anal fissures patients were treated using standardized scales measuring complaints severity from REALISE score. It was conducted at homeopathic hospitals in RBTSGHMCH Bihar India, during from mid-feb 2023 to mid-Nov 2023. Patients were intervened as per individualized homeopathic principles and followed up every fortnight up to 3 months.
Results: Total 40 were screened, 34 enrolled, 30 completed, 4 dropped out. Intention to treat population (n: = 30) was analyzed in the end. A ‘paired t-test’ was conducted to compare the effect of Individualized Homeopathic medicine at “0” month (Baseline) and after “3” months. The mean was reduced from 23.26 (SD 3.638) to 5.33 (SD 4.513). The reduction [t(29)=22.119, p<0.001, 2 tailed which less than p<0.05]. The 95% confidence interval for the mean difference ranges from 16.27516 to 19.59151. Here p values much less than P<0.01, Hence statistically highly significant.
Conclusion: Under classical homeopathic treatment, Anal fissures patients improved considerably in symptoms severity in REALISE scores. However, being observational trial, our study cannot provide efficacy data. Controlled studies are required. This study was approved by institutional ethics committees were obtained (IEC no. R.B.T.S ETHICS-53/21-24), and was not registered in CTRI.