International Journal of Homoeopathic Sciences

Obesity is a chronic metabolic disorder characterized by excessive fat accumulation due to hypertrophy and hyperplasia of adipose cells. According to the World Health Organization (2024), 16% of the global adult population lives with obesity, contributing to increased risk of cardiovascular diseases, diabetes, infertility, and other metabolic complications. This study evaluates the anti-obesity efficacy of Capsicum annuum prepared in decimal scale, a homoeopathic remedy known for its active component capsaicinoids, which possess thermogenic and fat-reducing properties. The study aims to assess its impact on body weight, BMI, and lipid profile over a 3-month period in obese patients (BMI 25-40 kg/m²). Plant extracts will be prepared via Soxhlet extraction and analyzed using GC-MS for phytochemical profiling. Fifteen patients will be enrolled following IRB approval under ethical guidelines, and clinical outcomes will be monitored through periodic visits, blood tests, and health assessments. The results are expected to validate the safety and cost-effectiveness of Capsicum annuum as a natural anti-obesity agent, promoting evidence-based use of homoeopathy in obesity management.