International Journal of Homoeopathic Sciences
Vol. 9, Issue 4, Part S (2025)
An in-vitro study on antibacterial activity of Croton tiglium and their potencies against Staphylococcus aureus
Haritha JR, Nirmal Franklin Antony J, Reshma AS, Shimmal Chenthik JP and Sreeja S
A common component of the body's microbiota, Staphylococcus aureus is a spherically shaped, Gram-positive bacteria that belongs to the Bacillota and is commonly found on the skin and in the upper airways. It is an anaerobe with facultative characteristics that can grow without oxygen and frequently tests positive for nitrate reduction and catalase. S. aureus typically functions as a symbiont of the human microbiota, but it can potentially turn into an opportunistic pathogen. It is frequently responsible for food poisoning, respiratory infections like sinusitis, and skin infections like abscesses. By generating virulence characteristics including strong protein toxins and the production of a cell- surface protein which binds and deactivates antibodies, pathogenic strains frequently encourage infections. Generally speaking, the skin and mucus membranes provide a strong defense against infection. However, S. aureus may enter the tissues underneath or the circulation if those barriers are compromised (for example, by trauma-induced skin injury or viral infection-induced mucosal damage). Abscesses, cellulitis, food poisoning, osteomyelitis, and septicemia are just a few of the many illnesses that S. aureus is a major cause. Approximately one-third of healthy people have these germs on their skin, in their pharynx, and in their noses. The purpose of this study is to assess Croton tiglium Q's antibacterial properties at 30 and 200 degrees Celsius against Staphylococcus aureus bacterial strains. The positive control was the antibiotic streptomycin, while the negative control was ethanol. The zone of inhibition demonstrated good antibacterial properties against the Staphylococcal aureus bacterial strains when tested for the various potencies of the bacteria.
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