International Journal of Homoeopathic Sciences

Background: Psoriasis is a chronic, immune-mediated dermatosis marked by erythematous, scaly plaques with fluctuating course and significant impact on quality of life. Individualized homoeopathic treatment supported by repertorial analysis aims to address both cutaneous and systemic dimensions of the disease.

Objectives

1. To assess the utility of the Synthesis repertory in selecting the simillimum for patients with psoriasis.
2. To formulate a practical homoeopathic management protocol for psoriasis.
3. To identify rubrics most frequently used in repertorization of psoriasis cases.
4. To delineate effective repertorial approach for psoriatic presentations.

Methods: A retrospective observational analysis of 30 psoriasis cases managed over 18 months in college OPD and peripheral OPD was conducted. Cases treated by repertorization with Synthesis Repertory 9.1 were included, and those managed with other repertories were excluded. Data were abstracted from standardized case records, PASI scores were calculated at baseline and last follow-up, and prescriptions were individualized using Synthesis repertory with RADAR software. Descriptive statistics and appropriate tests (including t test) were applied at 5% significance.

Results: Mean PASI reduced from 5.85 at first prescription to 2.67 at the end of follow‑up, corresponding to an average improvement of 3.18 points. Overall, 28 of 30 patients (93.3%) showed meaningful improvement, while 2 (6.7%) remained unimproved. Most cases shifted from moderate to mild disease category. Frequently prescribed remedies included Lycopodium, Calcarea carbonica, Hyoscyamus, Graphites, Pulsatilla, Natrum muriaticum and a range of less common medicines. Skin rubrics on eruptions with scaling and itching, with mental rubrics and food/drink generals, were most often utilized.

Conclusion: Individualized homoeopathic management of psoriasis guided by Synthesis repertory was associated with significant reduction in PASI scores and high response rates in this retrospective series. The repertorial approach centered on combined skin, mental and general rubrics appears clinically useful and warrants evaluation in prospective controlled studies.