Abstract: In homoeopathy, vast numbers of drugs are written in homoeopathic materia medica. Sometimes it leads to confusion in physician’s mind that which remedy they should prescribe in a case. Very often homoeopathic physicians prescribe polychrest drugs based on symptom similarity and they get wonderful results. But sometimes it is very difficult to find one drug which can cover the totality, due to paucity of characteristic symptom or due to suppression of complaints or due to advance pathological changes. In this situation we have to prescribe a drug based on present signs & symptoms and here rare remedies plays important role in treatment of patient. Rare remedies are not frequently used because its actions are limited to some specific organ or part of the body. E.g. Gun Powder, it has specific action on skin and it acts as an antiseptic drug. It is useful when Hepar Sulph and Silicea fails to cure abcess, boils etc.