International Journal of Homoeopathic Sciences

The process of dynamization, or potentization, is a hallmark of homoeopathy, converting inert medicinal substances into powerful therapeutic agents. While earlier editions of Hahnemann’s Organon of Medicine emphasized the centesimal scale, the sixth edition introduced a refined system — the fifty-millesimal (LM/Q) method of dynamization. Hahnemann regarded this as his perfected method, addressing the limitations of centesimal potencies by offering gentle, deep, and repeatable action. This article explores the preparation, advantages, and clinical significance of the fifty-millesimal method, alongside perspectives from homoeopathic stalwarts and its relevance in modern practice.